Spike Proteins May be for Life: Dr Mercola By Brian Simpson

I have mentioned this before, but Dr Mercola has done a detailed account of this: how long will the mRNA spike proteins last in the human body of those who have been jabbed? Given the array of vaccine injuries, and that many are long-term and we have not yet seen the last of them, and that the health authorities want to keep jabbing with new mRNA vaxxes now out, this could be a major concern to millions of people, if not the majority of people having had the vax, perhaps numerous times.

Research is indicting that there is no “off  switch” for the production of mRNA in the body. One study found that the mRNA spike protein was present in at least 50 percent of subjects for at least six months after injection, and the study was terminated at that point, so it is likely that the proteins would continue, as there is no mechanism for them to stop. It has been speculated that the spike protein may be integrated into human cells and/or bacteria present in the blood.   Research in 2022 found the mRNA in Pfizer’s vax could integrate into human cellular DNA by reverse transcription, at least as seen in a test-tube study.

It is early days yet, but it seems that the conspiracy theorists who saw the Covid vax scheme as a transhumanist attempt to begin to alter the human genome, may be right. We simply do not know there this diabolical experiment will lead.

 

https://articles.mercola.com/sites/articles/archive/2023/09/12/covid-jab-spike-protein.aspx

“How long will your body produce modified spike protein after the COVID jab? That’s been a question people have been asking ever since the rollout of the first mRNA shots.

A paper published in the Proteomics Clinical Applications journal in mid-August 20231 tried to answer that question, and it’s not great news, as the answer, for some people, as we said long before the jab was released, could be "indefinitely." What we can say for sure is that spike is being produced for far longer than "experts" initially believed.

Fact Versus Fiction

The idea behind the mRNA jabs was that the modified RNA would trigger temporary production of a spike protein similar to that of the wild-type SARS-CoV-2 spike to induce antibodies. We were told that mRNA is fragile and doesn’t last long, which is true of natural mRNA. The mRNA in the shots, however, has been modified to resist degradation.

As explained in a mid-August 2023 Proteomics Clinical Applications paper,2 the recombinant spike found in the mRNA COVID shots "is distinguishable from the wild-type protein due to specific amino acid variations introduced to maintain the protein in a prefused state."

And, while authorities admitted they didn’t know exactly for how long the mRNA would last, they insisted it certainly wouldn’t linger for more than a few days at most.3,4 In fact, to this day, the Centers for Disease Control and Prevention website falsely maintains that "The mRNA from the vaccines is broken down within a few days after vaccination and discarded from the body."5

Chronic immune activation can be a very serious problem, so you really don’t want your body to be producing antibodies daily for months at a time.

The spike protein is also responsible for the pathogenicity of COVID-19 and is the main driver of jab-related injuries and deaths,6 so you don’t want this spike protein to linger longer than what is necessary to trigger an initial antibody response. Unfortunately, that’s what we’re now finding.

Spike Detected for Up to Six Months

According to a recent investigation, published in the Proteomics Clinical Applications journal in mid-August 2023,7,8 recombinant spike protein was detectable in half the blood samples of jabbed individuals for at least 69 days, and up to 187 days (about six months).

To be clear, this doesn’t mean spike production ends at six months. That was just the end of the study period. What’s more, two of the proposed mechanisms of action, which I’ll review below, suggest spike production could continue indefinitely.

To make sure they were only measuring jab-related spike proteins and not spike protein from natural infection, the scientists used a mass-spectrometry test to detect a specific amino acid sequence — two prolines — found only in the jab-induced spike.

They also included two unjabbed control groups to make doubly sure — one consisted of unjabbed individuals who had never had COVID and had no antibodies; the other were unjabbed who’d had COVID and did have antibodies.

As expected, only those in the jabbed group had vaccine-derived spike protein in their blood. Only half of them had it, though, which is interesting considering Danish evidence suggesting that one-third of Pfizer’s shots were placebo. (The data for this claim were published in a March 2023 Letter to the Editor of the European Journal of Clinical Investigation.9)

So, to be clear, not everyone who got one or even more jabs will have spike production. Many, in this case half, have no detectable spike in their systems and are therefore unlikely to experience any adverse effects. That’s the good news. The bad news is that the other half do have persistent spike production, and in some, it may never stop.

Potential Mechanisms Behind Persistent Spike Production

The Proteomics Clinical Applications paper goes on to present three "likely" or potential mechanisms behind the persistent spike production — some of which are worse than others:10

1."It is possible that the mRNA may be integrated or re-transcribed in some cells.

2.It is possible that pseudo-uridines at a particular sequence position ... induce the formation of a spike protein that is always constitutively active ...

3.It is possible that the mRNA-containing nanoparticle will be picked up by bacteria normally present at the basal level in the blood ..." (These bacteria would then continuously produce spike protein)

Disturbingly, all three mechanisms could result in never-ending spike production (or spike activity, for as long as the spike remains in the body). Now, if spike production can end up being lifelong in some individuals, what does that mean for people who have received multiple shots containing several different mRNA sequences?

Pfizer mRNA Appears to Have Ability to Reprogram Human DNA

If mRNA is integrated or re-transcribed in cells (the first hypothesis above), that means the modified, synthetic mRNA in the jab can become part of and permanently rewrite a section of your DNA with instructions to produce the spike.

In addition to affected cells producing spike indefinitely, this genetic alteration may also be transferred to your offspring, the effects of which are wholly unknown. We could expect affected infants and children to have chronic health problems, however, and likely impaired immune response to coronaviruses, including those responsible for the common cold.

Disturbingly, the reverse transcription hypothesis has already been demonstrated in in-vitro experiments,11 so it’s not as far-fetched as fact checkers — or even the CDC — would like you to believe. According to the CDC, "These vaccines do NOT enter the nucleus of the cell where our DNA (genetic material) is located, so it cannot change or influence our genes."12 But in vitro experiments prove otherwise.

In vitro research published in 2022 found the mRNA in Pfizer’s COVID jab could integrate into human cellular DNA by reverse transcription.

In February 2022, a research paper13 titled "Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line" described how the mRNA is being integrated into human cellular DNA by reverse transcription — something that was absolutely not supposed to happen and was written off as a "conspiracy theory."

In a nutshell, what this study found was that the genetic code of Pfizer’s COVID jab was reverse transcribed into and became part of the human liver cells used. Somehow, the shot triggers cells to produce a natural reverse transcriptase enzyme called LINE-1, which allows this reverse transcription to take place.

Genetic Integration Can Occur Through Other Means as Well

Incidentally, studies14,15 have also shown that RNA from SARS-CoV-2 can be reverse transcribed into the genome of virus-infected cells, and if viral RNA can do it, why not the synthetic RNA?

On top of that, the COVID shots have also been found to be contaminated with DNA,16 and this too could lead to genomic integration and alteration, without the need for reverse transcription. As explained by Igor Chudov:17

"Normally ... the cell nucleus, where the DNA is, expresses certain DNA code based on conditions of the cell, and produces natural, human messenger RNA.

That messenger RNA travels out of the nucleus, where it is expressed into proteins needed for cell building. This is how growing organisms express different genetic programs to grow muscle cells or brain cells, etc. This process is called ‘transcription.’

For many years, Central Dogma of Molecular Biology stated that the ‘reverse transcription’ — moving genetic code from RNA back into the sacred cellular nucleus and recoding the DNA — was impossible.

Eventually, scientists realized that it is possible under various conditions ... To effect reverse transcription, enzymes called ‘reverse transcriptases’ are needed. One of them is called LINE-1. Apparently, per [the] study, the Pfizer mRNA vaccine causes cells to produce that LINE-1 enzyme ...

As I explained in response to a questioner: Pfizer mRNA vaccine changes our genetic code that determines how our organisms operate, that you inherited from your mom and dad.

Now your DNA was changed from what your mom and dad gave you, by adding a little mysterious ‘edit’ from Pfizer. Your organism acts in accordance with your DNA program, and now, well, the program has been hacked and modified by Pfizer.

Considering that Sars-Cov-2 ‘spike protein’ has cancer code from Moderna 2017’ patent 9,587,003,18 it is imperative to find out the implications of this reverse transcription, and whether the vaccinated now have any undesirable genetic code embedded into their DNA.

Of particular interest is whether this mRNA-induced reverse transcription affects the ‘germ line,’ such as eggs and sperm cells, and whether it also affects the fetus of pregnant mothers."

Can Chronic Spike Production Explain Immune Tolerance?

As noted in Chudov’s August 31, 2023, Substack article, in which he reviews the ramifications of the hypotheses put forth in the Proteomics Clinical Applications paper,19 Nos. 1 and 2 may also explain why jabbed individuals are so prone to COVID reinfection.

In short, by producing spike protein for months and perhaps years on end, your body starts to view the SARS-CoV-2 virus as an environmental irritant rather than the potentially lethal invader that it is. This is called immune tolerance and is how allergies typically work.

Basically, your body simply ignores the irritant, and you suffer the symptoms for as long as the irritant is present. However, immune tolerance can become deadly when your body is assaulted by replicating pathogens and fails to launch an appropriate immune response.

 

 

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Thursday, 13 June 2024

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