Spike Proteins and DNA Damage By Brian Simpson
We have covered this issue before, of the study that reported how the spike protein harms cellular DNA repair. Here is the abstract of the study for the more technically minded anti-vaxxers.
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8538446/
Viruses. 2021 Oct; 13(10): 2056.
Published online 2021 Oct 13. doi: 10.3390/v13102056
PMCID: PMC8538446
PMID: 34696485
SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro
Hui Jiang1,2,* and Ya-Fang Mei2,*
Oliver Schildgen, Academic Editor
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS–CoV–2) has led to the coronavirus disease 2019 (COVID–19) pandemic, severely affecting public health and the global economy. Adaptive immunity plays a crucial role in fighting against SARS–CoV–2 infection and directly influences the clinical outcomes of patients. Clinical studies have indicated that patients with severe COVID–19 exhibit delayed and weak adaptive immune responses; however, the mechanism by which SARS–CoV–2 impedes adaptive immunity remains unclear. Here, by using an in vitro cell line, we report that the SARS–CoV–2 spike protein significantly inhibits DNA damage repair, which is required for effective V(D)J recombination in adaptive immunity. Mechanistically, we found that the spike protein localizes in the nucleus and inhibits DNA damage repair by impeding key DNA repair protein BRCA1 and 53BP1 recruitment to the damage site. Our findings reveal a potential molecular mechanism by which the spike protein might impede adaptive immunity and underscore the potential side effects of full-length spike-based vaccines.”
This is consistent with the case made by Whitney, that the vaxxes are a lab-created bioweapon for a depopulation agenda.
“If someone wished to kill a significant portion of the world’s population over the next few years, the systems being put in place right now would enable it.” Dr. Mike Yeadon, former Pfizer Vice President
“And this is the spirit of the antichrist, of which you have heard is coming; and now is already in the world.” 1 John 4:2–3
Question– Does the Covid-19 vaccine damage the immune system?
Answer– It does. It impairs the body’s ability to fight infection, viruses and disease.
Question– If that’s true, then why haven’t more people died after getting vaccinated?
Answer– I’m not sure what you mean? The vaccine has killed more people than any vaccine in history. “So far, in the United States, the death toll is three times higher than the total of all vaccines in the last 35 years.” That’s simply astonishing. We’ve also seen a steady rise in all-cause mortality and excess deaths in the countries that launched mass vaccination campaigns earlier in the year. Sometimes the increase is as much as 20 percent over the five-year average. That is a massive spike in fatalities, and it’s largely attributable to the vaccine. So, what do you mean when you say, “Why haven’t more people died”? Did you expect to see people clutching their hearts and dropping dead after getting jabbed? That’s a very naive understanding of how the injection works. (See: “COVID Deaths Before and After Vaccination Programs”, You Tube; 2 minutes)
Question– All I’m saying is that the percentage of people that have died is quite small compared to the tens of millions that have been vaccinated.
Answer– And all I’m saying is that if the vaccine is lab-generated pathogen– and I think it is– then it certainly was not designed to kill people on the spot. It was engineered to produce a delayed reaction that gradually but relentlessly erodes the health of the vaccinee. In other words, the full impact of the blood clots, bleeding, autoimmune issues and other vaccine-generated injuries will only be fully felt at a later date via increasing incidents of heart attacks, strokes, vascular illness and even cancer. (Check out the “latest trend of cardiac attendances by Scottish Ambulance Service – this is *excess* above the 2018/19 norm. Huge spike in summer, 500 ambulance calls per week above normal, mainly age 15-64. Was settling, then spike up again since late October.” Scottish Unity – Edinburgh Group)
Answer– The chart above shows why cardiac issues have garnered a lot of attention lately, but the damage to the immune system is even more concerning.
Question– Can you explain what you mean without getting too technical?
Answer– I can do better than that. I can give you a short clip from an article that covers the latest research. Check it out:
“A Swedish lab study (titled “SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro“, NIH) released in mid-October found that the spike protein… enters the nucleus of cells and significantly interferes with DNA damage-repair functions compromising a person’s adaptive immunity and perhaps encouraging the formation of cancer cells….
“Mechanistically, we found that the spike protein localizes in the nucleus and inhibits DNA damage repair,” they wrote. “Our findings reveal a potential molecular mechanism by which the spike protein might impede adaptive immunity and underscore the potential side effects of full-length spike-based vaccines.” (“Spike protein in COVID virus and shots weakens immune system, may be linked with cancer: Swedish study“, Lifesite News)
What the researchers found is that the spike protein blocks production of the enzymes that are needed to repair broken DNA which, in turn, prevents the “proliferation” of B and T cells that are needed to fight infection.
Question– Can you explain that in plain English?
Answer– Sure. It means the vaccine short-circuits your immune system which clears the way for infection, disease and an early death. Maybe, you think you can have a long and happy life with a dysfunctional immune system, but I think you’re wrong. The immune system is the shield that protects you from all-manner of potentially-lethal viruses, bacteria and infections. It is not just the first-line of defense, it’s the only line of defense. Absent the full protection of B and T cells to fight-off foreign intruders, the prospects for survival are miniscule at best.
In order to underscore that point, check out this video of British Funeral Director, John O’ Looney, who has provided regular updates on what he is seeing on the ground 10 months following the vaccination rollout. It’s a disturbing account of the catastrophe that is now unfolding before our eyes:
(30 second mark) “So what we’re seeing is an unnaturally large number of deaths due to heart attack, stroke, aneurism; and these are all the result of thrombosis … Embolisms in the lungs the legs, various places that are causing these deaths that are well documented by the local coroners and well-documented across the country. And no one seems to be concerned about the alarming rise of (blood clots) I’ve seen more in this year than in the last 14 years….
That’s one kind of death we’re seeing, the other kind is the people that are getting sick now as their immune systems finally give up. So, they’ve had the jabs maybe 6 or 8 months ago, and it’s been eating away at their immune system, and now they’re struggling to fight off things like the common cold. So, we’re in winter and there are colds and flus around and these people can’t fight them off. The government are very quick to label it “Omicron”…but they are sick with the common cold. Their immune systems are decimated. It’s much like a cancer patient, who goes through chemotherapy and it decimates their immune system. And they have to be very careful because the common cold or flu can kill them. And this is what we’re seeing now…
We’re nearly 12 months since the first jabs began, so their immune systems are falling apart; that is the reality and that’s what I’m seeing... and they can’t cope with a cold anymore. … When I went to the meeting in Westminster in September, the scientist predicted that this is what would happen and, lo-and-behold, that’s what happening. The people are getting sick and dying….. It’s frightening.” (“Omicron is ‘vaccine injury’; it’s nothing more than that.” John Looney, Rumble)
Is he right? Is the uptick in fatalities NOT another wave of Covid but the knock-on effects of a cytotoxic injection that targets the immune system leaving millions of people defenseless against routine infections and disease?
It sounds feasible and it certainly fits with the depopulation agenda which requires a hybrid biologic that doesn’t kill its target outright but basically dismantles the critical defense systems that make human survival possible. By disguising a “killer protein”
as a harmless antigen, our pandemic managers have been able to access the bloodstreams of millions of people allowing them to insert a ticking time-bomb that ravages crucial T and B-cell populations leaving victims vulnerable to whatever bug happens to be circulating in the population. As Looney notes, scientists warned of this very outcome when mass vaccination was first proposed. Naturally, opposing views were ignored and censored. Here’s more from a pre-print research paper on the medRxiv server. It helps to explain the vaccine’s impact on the immune system:
“Researchers in The Netherlands and Germany have warned that Pfizer-BioNTech’s … (COVID-19) vaccine induces complex reprogramming of innate immune responses that should be considered in the development and use of mRNA-based vaccines…. Following vaccination, innate immune cells had a reduced response to toll-like receptor 4 (TLR4), TLR7 and TLR8 – all ligands that play an important role in the immune response to viral infection….
“Multiple studies have shown that long-term innate immune responses can be either increased (trained immunity) or down-regulated (innate immune tolerance) after certain vaccines or infections.”…
These results collectively demonstrate that the effects of the BNT162b2 vaccine go beyond the adaptive immune system.. The BNT162b2 vaccine induces reprogramming of innate immune responses as well, and this needs to be taken into account.”…(“Research suggests Pfizer-BioNTech COVID-19 vaccine reprograms innate immune responses”, New-Medical net)
How many people would have gotten vaccinated if they’d known it would reprogram their immune system?
Probably, no one, which is why our public health officials never broach the topic. Anything that veers even slightly from the “vaccines are good for you” narrative is omitted from mainstream coverage and erased on social media. But aren’t people entitled to know what’s going on, what is being injected into their bodies, and what impact it will have on their lives and health? Isn’t that what is meant by “informed consent” or is that another casualty of the rush to inoculate all people on planet earth? Here’s a clip from a short interview with pathologist, Dr. Ryan Cole:
“When we give these shots, we can see the types of white blood cells in the body… and you have a broad array of immune cells that work together to fight off viruses and keep cancers in check. We’re already seeing the signals in the laboratory of decreases in critically important T-cells you need… in your innate immune system. These are the Marines in your body; fighting off viruses fighting cancer…. But what we’re seeing in the laboratory after people get these shots, we’re seeing a very concerning locked-in, low profile of these important killer T-cells that you want in your body. (CD8 cells) And what they do, is keep all other viruses in check.
What am I seeing in the laboratory? I’m seeing an uptick of Herpes family viruses, I’m seeing Shingles, I’m seeing Mono, I’m seeing a huge uptick in human papilloma virus… We are literally weakening the immune systems of these individuals.
Most concerning of all, is there’s a pattern of these types of immune cells in the body that keep cancer in check. Since, January 1, (in the laboratory) I’ve seen a 20X increase of endometrial cancer over what I see on an annual basis.” (“Pathologist Ryan N Cole of the Mayo Clinic on What We Are Seeing In Lab Results”, Rumble; 2 minutes)
“Herpes, Shingles, Mono, and even cancer!” What the heck is going on? This can’t be true, can it?
Yes, it is true; immuno-suppression leads to all kinds of terrible health outcomes. Some readers might recall how Canadian vaccinologist Dr Byram Bridle made similar claims in an interview just a few weeks ago. Here’s what he said:
“What I’ve seen way too much of is people who had cancers that were in remission, or that were being well controlled; their cancers have gone completely out of control after getting this vaccine. And we know the vaccine causes a drop in T-cell numbers, and those T-cells are part of our immune system and they are part of the critical weapons our immune system has to fight off cancer cells; so there’s a potential mechanism there. All I can say, is I’ve had way too many people contact me with these reports for me to feel comfortable. I would say that is my newest major safety concern, and it’s also the one that’s going to be the most under-reported in the adverse data base, because if someone has had cancer before the vaccine, there’s no way public health officials will ever link it to the vaccine.” (“Dr Byram Bridle speaks”, Bitchute, :55 second-mark)
Once again, how many people would have decided to get vaccinated if they knew that it could trigger a flare-up of dormant viruses or cancers in remission? Who would take that risk?
But they don’t know they’re taking a risk, do they, because they haven’t been told the truth. And the reason they haven’t been told the truth is because they are a target in a war of extermination that is being waged on them. Sometimes it’s very hard for people to admit to what they know to be the truth, but the truth is plain to see. Our pandemic managers and their foot-soldiers in the media, public health and government want to do us harm, want to inject us with a mysterious substance that will wreak havoc on our immune systems and shorten our lives. This isn’t just a struggle for personal freedom or bodily autonomy, it’s a battle for survival. We are defending our right to live. Here’s more from Viral Immunologist Dr. Jessica Rose:
“There are studies coming out now, and there are ample signs in the adverse events data, that these products (Covid vaccines) are not only immuno-modulating the immune system and causing hyper inflammation; there are signs now that they are very negatively effecting CD8 T-cell populations. For those who don’t know, this is extremely bad news. It’s only on a few people so far, but the data does not look good so far. These T-cells are the so-called “killer cells”. Their job…is to kill virally infected cells that are showing foreign markers on their surface. So, if these populations are depleted, then that is very bad news, because we don’t have a population of cells in the acquired immune system to remove virally-infected cells.…
There are clear signs that are starting to emerge, that there is an “immunity deficiency syndrome” coming about as a result of these products (vaccines) As a result of hyper-stimulation…T-cells being (diminished), and the ever-presence of repeated injections of a cytotoxic protein… I would never, ever recommend that someone who is immuno-compromised to ever go near these things, because I can almost guarantee you, that your condition is going to get worse. Another thing we’re seeing in VAERS is cancers coming out of remission and alot of doctors are reporting this on the ground. And–by the way– this has never happened before, not on this scale; not even close… So, there’s something going on here that warrants further investigation, and it doesn’t look good.” (“Viral Immunologist Dr. Jessica Rose explains the concerning information emerging about the compromised immunity of the vaccinated“, Odysee)
Can you see the pattern yet? Can you see how they’re all saying the same thing? Why is that, do you think?
It’s because it’s the truth, the pure, unvarnished truth.
The point we’re trying to make cannot be overstated: The vaccine is a man-made, lab-generated bioweapon that disables the body’s critical defense system which increases one’s susceptibility to disease by many orders of magnitude. With each additional injection, one is less capable of mounting a sufficient response to routine infections, flus or viruses. That’s going to lead to a tsunami of sickness that will likely overwhelm our public health system and plunge the country deeper into crisis. Is that the plan? Is that what our globalist overlords have in store for us?
We’ll see. Now check out this last clip from video by vaccinologist, Geert Vanden Bossche:
“The first thing I would like to highlight is that Covid-19 is not a disease of healthy people. People who are in good health have a healthy innate immune system that can deal with a number of respiratory viruses without any problem. These people are not only protected against the disease but can even–in many cases– prevent infection. These are people who can contribute to sterilizing immunity and to herd immunity which is very, very important. So, listen: Never, ever allow anyone or anything to interfere or suppress your innate immune system. You can do a bad job yourself by leading an unhealthy life, that is going to suppress your innate immunity, but even worse, is vaccine-induced antibodies that do suppress your innate immunity. And these vaccinal antibodies cannot substitute for it because they lose their efficacy against the virus, and become less and less effective. In contrast to the innate antibodies, they cannot prevent infection, they cannot sterilize the virus. Therefore, they do contribute to herd immunity….
If we suppress these innate antibodies in children, it could lead to autoimmune diseases. This is an absolute “No go.” We cannot vaccinate our children with these vaccines. The suppression of innate immunity is already a problem among vaccinees, and they are, indeed, going to have a difficult time controlling a number of diseases, not just Covid-19, but other diseases too …and it will require a very dramatic change in the strategies to help the vaccinees–and my heart goes out to them–because they will need extensive treatment in many cases...
… Boosting them–which means giving them a third dose– is absolutely insane, because what it will do, is increase the immune pressure of the vaccinal antibodies, on their innate immunity. So boosting is absolute nonsense; it is dangerous and should not be done….
So, what does the science tell us? It tells us that it’s innate immunity that will protect us, not the vaccine.” (“Geert Vanden Bossche on Vaccines and the suppression of innate immunity”, Rumble)
So, we now know that– along with the blood clots, the bleeding, the heart attacks, the strokes, the vascular and neurological diseases– the vaccine is also designed to eviscerate the system that protects us from illness and death, the immune system. How steeped in denial one must be not to see the evil that is now among us.
Also see: Dr. Nathan Thompson– The Covid Vaccine induces Autoimmunity, Odysee
https://odysee.com/@EndYourSlavery:8/My-Jaw-DROPPED-when-I-Tested-Someone’s-Immune-System-After-the-2nd-Jab:d
And this: Vaccine Acquired Immune Deficiency Syndrome (VAIDS): ‘We should anticipate seeing this immune erosion more widely'” Americas Frontline Doctors https://americasfrontlinedoctors.org/news/post/vaccine-acquired-immune-deficiency-syndrome-vaids-we-should-anticipate-seeing-this-immune-erosion-more-widely/
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