mRNA Vaxxes Inhibit Innate and Adaptive Immune Responses By Brian Simpson
A new pre-print paper at bioRxiv, gives further evidence of possible harms of the mRNA vaxxes, showing effects upon innate, and adaptive immune responses. The innate immune system is the body's first line of defense against germs entering the body, and consists of:
- Protection offered by the skin and mucous membranes.
- Protection offered by the immune system cells (defense cells) and proteins.
The adaptive immune system responses are carried out by white blood cells called lymphocytes. There are such responses—antibody responses and cell-mediated immune responses, and they are carried out by different classes of lymphocytes, called B cells and T cells. Pre-exposure to mRNA-LNPs (lipid nanoparticles), or its LNP components has harmful effects upon both categories of immune response. “LNPs led to long-term inhibition of the adaptive immune responses, which the use of adjuvants could overcome.” This, of course, has been denied by the mainstream Covid narrative from the beginning.
“Microbiologists at Thomas Jefferson University in Philadelphia, Pennsylvania recently studying mRNA-based COVID-19 vaccines suggests their work links to evidence that pre-exposure to mRNA-LNPs (lipid nanoparticles), or its LNP component impacts innate and adaptive immune responses. For example, the authors write in a preprint uploaded to bioRxiv, “LNPs led to long-term inhibition of the adaptive immune responses, which the use of adjuvants could overcome.” Yet the authors also shared that mice pre-exposed to mRNA-LNPs can pass down the acquired immune traits to their offspring as well as find that resistance of mice to heterologous infections with influenza boosted while Candida albicans decreased. The authors report “general neutropenia in the mRNA-LNP exposed mice.”
The authors report that when exposing mice to mRNA-LNPs, this can actually “pass down the acquired immune traits to their offspring.” By introducing “long-term immunological changes” impacting adaptive immune responses and heterologous protection against infections—some passed down by offspring, the Thomas Jefferson University scientists articulate more research is needed into not only the mechanisms of action for the observed effects, but also the overall impact on human health.
Not yet peer reviewed, this experimental evidence suggests that pre-exposure to mRNA-LNPs or related LNP components impacts innate and adaptive immune response.”
https://www.biorxiv.org/content/10.1101/2022.03.16.484616v2
ABSTRACT
Hundreds of millions of SARS-CoV-2 mRNA-LNP vaccine doses have already been administered to humans. However, we lack a comprehensive understanding of the immune effects of this platform. The mRNA-LNP-based SARS-CoV-2 vaccine is highly inflammatory, and its synthetic ionizable lipid component responsible for the induction of inflammation has a long in vivo half-life. Since chronic inflammation can lead to immune exhaustion and non-responsiveness, we sought to determine the effects of pre-exposure to the mRNA-LNP on adaptive immune responses and innate immune fitness. We found that pre-exposure to mRNA-LNPs or LNP alone led to long-term inhibition of the adaptive immune responses, which could be overcome using standard adjuvants. On the other hand, we report that after pre-exposure to mRNA-LNPs, the resistance of mice to heterologous infections with influenza virus increased while Candida albicans decreased. The diminished resistance to Candida albicans correlated with a general decrease in blood neutrophil percentages. Interestingly, mice pre-exposed to the mRNA-LNP platform can pass down the acquired immune traits to their offspring, providing better protection against influenza. In summary, the mRNA-LNP vaccine platform induces long-term unexpected immunological changes affecting both adaptive immune responses and heterologous protection against infections. Thus, our studies highlight the need for more research to determine this platform’s true impact on human health.
Authors Summary We bring experimental evidence that pre-exposure to mRNA-LNPs or its LNP component affects innate and adaptive immune responses. Pre-exposure to mRNA-LNPs led to long-term inhibition of the adaptive immune responses, which the use of adjuvants could overcome. On the other hand, we report that after pre-exposure to mRNA-LNPs, the resistance of mice to heterologous infections with influenza virus increased while Candida albicans decreased. We also detected a general neutropenia in the mRNA-LNP exposed mice. Interestingly, mice pre-exposed to mRNA-LNPs can pass down the acquired immune traits to their offspring. In summary, the mRNA-LNP vaccine platform induces long-term immunological changes that can affect both adaptive immune responses and heterologous protection against infections, some of which can be inherited by the offspring. More studies are needed to understand the mechanisms responsible for these effects and determine this platform’s impact on human health.”
Comments