Get Ready for More Virulent and Lethal Versions of SARS-CoV-2, Cooked in a Lab as Well! By Brian Simpson
It is hard to believe, but then again, maybe not after all we have been through with Covid, but Dr Frankenstein scientists across the globe are cooking up much more dangerous versions of SARS-CoV-2. In particular, scientists have passed the live virus through plasma obtained from a patient who had recovered from Covid, finding to their Satanic delight that mutations occurred enabling the virus to evade the antibodies. It is most likely that the virus would also escape the magic vaccines as well. Apparently a lab release of this killer virus has not yet occurred, but no doubt it will be the next Big Thing in the depopulation agenda.
“If SARS-CoV-2 has frazzled your nerves, I have bad news for you. Scientists are already cooking up more virulent and lethal versions.
In a Jan. 22 Twitter post, biotech entrepreneur Yuri Deigin highlighted a study posted on the preprint server bioRxiv at the end of December 2020, saying:
“Ok, the prize for the craziest and most dangerous gain-of-function research goes out to Italian virologists who took SARS[-CoV-]2 and passaged it in vitro in the presence of neutralizing antibodies. It quickly obliged and mutated to escape them. Yay for a novel, more dangerous SARS3!”
“Passaging” refers to a genetic engineering technique where a virus is grown in a series of different animal tissue cultures. With each “pass,” the virus will mutate slightly, gaining different functions.
Serial passaging allows virus to jump species
As just one example, a potential outcome of this somewhat crude technique (considering the genetic engineering technology now available) would be that the virus could gain the ability to infect a host species it could not infect before. Some experts have speculated that this might be one way in which SARS-CoV-2 was created.
In an in-depth article published in New York magazine Jan. 4, Nicholson Baker reviewed the history of viral gain-of-function research, providing the following example of serial passaging:
“Baric … described in this early paper how his lab was able to train a coronavirus, MHV, which causes hepatitis in mice, to jump species, so that it could reliably infect BHK (baby-hamster kidney) cell cultures.
“They did it using serial passaging: repeatedly dosing a mixed solution of mouse cells and hamster cells with mouse-hepatitis virus, while each time decreasing the number of mouse cells and upping the concentration of hamster cells.
“At first, predictably, the mouse-hepatitis virus couldn’t do much with the hamster cells, which were left almost free of infection, floating in their world of fetal-calf serum.
“But by the end of the experiment, after dozens of passages through cell cultures, the virus had mutated: It had mastered the trick of parasitizing an unfamiliar rodent. A scourge of mice was transformed into a scourge of hamsters …”
Scientists have created coronavirus that escapes antibodies.
So, what exactly have they come up with now? As summarized by Deigin, researchers serial passaged live SARS-CoV-2 in plasma obtained from a recovered COVID-19 patient that had a high amount of neutralizing antibodies in it.
For clarification, you have two types of antibodies. Neutralizing antibodies are, as the name implies, antibodies that neutralize (kill) viruses and prevent infection, whereas binding antibodies cannot prevent infection.
The neutralizing antibodies in the plasma successfully and completely neutralized the virus during the first seven passages, but then, the virus mutated to evade the antibodies. As explained by the authors:
“The plasma fully neutralized the virus for 7 passages, but after 45 days, the deletion of F140 in the spike N-terminal domain (NTD) N3 loop led to partial breakthrough. At day 73, an E484K substitution in the receptor-binding domain (RBD) occurred, followed at day 80 by an insertion in the NTD N5 loop containing a new glycan sequon, which generated a variant completely resistant to plasma neutralization.”
“In other words, they created a SARS-CoV-2 variant that bypasses acquired immunity and negates the immunity you normally would have after recovering from the infection. As such, it could be extremely lethal.
“Computational modeling predicts that the deletion and insertion in loops N3 and N5 prevent binding of neutralizing antibodies,” the authors say, adding:
“The recent emergence in the United Kingdom and South Africa of natural variants with similar changes suggests that SARS-CoV-2 has the potential to escape an effective immune response and that vaccines and antibodies able to control emerging variants should be developed.”
Selective pressure of vaccination may pose a problem
Now, further down in the paper, they point out that the reason they did this study was to determine “whether the authentic virus, under the selective pressure of the polyclonal immune response in convalescent or vaccinated people, can evolve to escape herd immunity and antibody treatment.”
Since the virus can mutate to evade neutralizing antibodies, then it could potentially mutate under the “selective pressure” of vaccination as well, which in turn raises the question: If we mass vaccinate, will we end up with a more lethal virus?
The solution these researchers seem to propose is to start thinking about vaccinating people for emerging SARS-CoV-2 variants, meaning we may need to develop a new vaccine — much like the seasonal flu vaccine — to match the circulating strains of each season.
Considering the first COVID-19 mRNA vaccines (which are most accurately described as gene therapy) are wreaking absolute havoc on people’s health already, the idea of implementing a twice-a-year gene-therapy regimen against COVID-19 strikes me as assured destruction of the human race.
Is SARS-CoV-2 result of gain-of-function research in Wuhan?
Jamie Metzl is a geopolitics expert, World Health Organization adviser and senior fellow at the Atlantic Council. Jan. 4 CBS News interviewed him about the “conspiracy theory” that SARS-CoV-2 was created in a biosecurity level 4 laboratory in Wuhan, China. Metzl believes the COVID-19 pandemic is the result of an accidental leak from that lab.
This, he says, is a logical conclusion based on the facts before us. First, Wuhan is far from the southern part of China where horseshoe bats (the supposed source host) exist.
Second, the Wuhan Institute of Virology (WIV) was known to have performed controversial gain-of-function research on bat coronaviruses and, according to U.S. diplomats who had visited the lab in 2018, significant safety shortcomings were apparent.
Third, SARS-CoV-2’s closest relative (RaTG13) has been traced back to samples collected in 2012 from miners sickened after working in an abandoned mine in Mojiang. There’s no trace of the virus anywhere between 2012 and 2019, until it suddenly caused an outbreak in Wuhan.
Lastly, “We see this massive Chinese cover-up,” Metzl says, “destroying samples, shutting off access to databases, imprisoning journalists [and] silencing scientists.”
On top of that, Metzl points out that scientists working at the WIV have been unable to account for all the viruses in their database, and level 4 biosecurity laboratories around the world have experienced many safety breaches in the past.”
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