Covid critics have focused upon the ill-effects the jabs had had upon female reproduction, but until now there has not been much research on the effects of the shots upon male reproduction. One paper has found that there is a “temporary” impairment of sperm quantity and quality from the jabs. How will this pan out? Will the next discovery be that the effects are even longer? With all the threats at present to sperm, human sperm might become as endangered as any species, only this one, this time, affects our survival.
“Covid-19 vaccination BNT162b2 temporarily impairs semen concentration and total motile count among semen donors
Itai Gat,Alon Kedem,Michal Dviri,Ana Umanski,Matan Levi,Ariel Hourvitz,Micha Baum
https://doi.org/10.1111/andr.13209
CAPSULE: A retrospective longitudinal multicenter comparison reveals temporary sperm concentration reduction 3 months post BNT162b2 vaccination and later recovery. Semen volume and motility remain stable.
This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as https://doi.org/10.1111/andr.13209
Abstract
Background
The development of covid-19 vaccinations represents a notable scientific achievement. Nevertheless, concerns have been raised regarding their possible detrimental impact on male fertility
Objective
To investigate the effect of covid-19 BNT162b2 (Pfizer) vaccine on semen parameters among semen donors (SD).
Methods
37 SD from three sperm banks that provided 220 samples, were included in that retrospective longitudinal multicenter cohort study. BNT162b2 vaccination included two doses, and vaccination completion was scheduled 7 days after the second dose. The study included four phases: T0 – pre-vaccination baseline control, which encompassed 1–2 initial samples per SD; T1, T2 and T3 – short, intermediate, and long terms evaluations, respectively. Each included 1–3 semen samples per donor provided 15–45, 75-120, and over 150 days after vaccination completion, respectively. The primary endpoints were semen parameters. Three statistical analyses were conducted: 1) generalized estimated equation model; 2) first sample and 3) samples' mean of each donor per period were compared to T0.
Results
Repetitive measurements revealed −15.4% sperm concentration decrease on T2 (CI -25.5%–3.9%, p = 0.01) leading to total motile count 22.1% reduction (CI -35% - -6.6%, p = 0.007) compared to T0. Similarly, analysis of first semen sample only and samples' mean per donor resulted in concentration and TMC reductions on T2 compared to T0 - median decline of 12 million/ml and 31 million motile spermatozoa, respectively (p = 0.02 and 0.002 respectively) on first sample evaluation and median decline of 9.5×106 and 27.3 million motile spermatozoa (p = 0.004 and 0.003, respectively) on samples' mean examination. T3 evaluation demonstrated overall recovery. Semen volume and sperm motility were not impaired.
Discussion
This longitudinal study focused on SD demonstrates selective temporary sperm concentration and TMC deterioration three months after vaccination followed by later recovery verified by diverse statistical analyses.
Conclusions
Systemic immune response after BNT162b2 vaccine is a reasonable cause for transient semen concentration and TMC decline. Long-term prognosis remains good.”