The article "What We Now Know About COVID Vaccine Shedding" by A Midwestern Doctor (published March 1, 2026, on Substack) is a deep dive into the author's perspective that COVID-19 vaccine shedding is a real and under-recognized phenomenon. The author, a physician pseudonymously writing under "A Midwestern Doctor," has compiled extensive anecdotal reports, reader submissions (over 1,500 cases), and select studies to argue that unvaccinated individuals can experience symptoms from proximity to recently vaccinated people, primarily via mRNA vaccines like Pfizer and Moderna.
The piece asserts shedding occurs consistently and predictably, strongest in the first few days to weeks after vaccination or boosters (peaking around 3 days to 4 weeks post-shot, sometimes lasting months). The primary mechanism proposed is exosome-mediated transmission: vaccinated cells produce spike protein-laden exosomes (small vesicles) that can be exhaled, secreted in sweat/saliva/breast milk, or transmitted via contact (e.g., hugs, shared objects like sheets). These exosomes allegedly carry spike protein or even mRNA fragments, triggering inflammatory responses in sensitive unvaccinated people.
Other speculated routes include:
Respiratory (proximity or shared air).
Skin contact or fomites.
Rarely, secondary shedding (from exposed unvaccinated to others).
The author notes mRNA vaccines differ from traditional ones (no live virus), but persistent spike production and exosome packaging make shedding plausible, unlike debunked early claims of impossibility. Spike protein persistence in blood (up to 709 days in some studies) supports longer-term effects.
Evidence Presented
Anecdotal/Reader Reports: Hundreds of consistent stories from the author's practice, Pierre Kory's network, online groups, and comments. Examples include unvaccinated people developing symptoms after close contact (e.g., family, coworkers, massages), pets affected, or nurses avoiding vaccinated patients.
Menstrual Effects: A key focus, with a peer-reviewed study (after delays/publication blocks) showing shedding-linked irregularities (e.g., heavy bleeding, cramps in postmenopausal women, decidual casts). MyCycleStory survey data (thousands of women) reported high rates of changes from proximity.
Other Symptoms in Exposed Unvaccinated: Often temporary/milder than direct vaccine injuries but overlapping — flu-like illness, headaches, fatigue, rashes, tinnitus, nosebleeds, shingles/herpes reactivation, palpitations, hair loss, clots, immune suppression, and rarer severe outcomes (e.g., heart issues, pneumonia).
Supporting Studies/Observations: Exosome research showing spike increase post-vaccination; mRNA in breast milk; spike antibodies in unvaccinated children of vaccinated parents; gene therapy precedents requiring shedding studies (unlike COVID vaccines); microbiome alterations post-vaccination.
The author emphasises patterns across datasets make shedding "very real" and calls for mRNA vaccine withdrawal due to risks, especially to unvaccinated/sensitive groups. Mitigation suggestions include avoiding shedders during peak windows, spike-detox protocols (e.g., DMSO-treatable inflammation), or isolation.
Mainstream scientific consensus holds that COVID-19 vaccine shedding (of mRNA, spike protein, or components causing illness) is not biologically plausible or supported by evidence. mRNA vaccines do not contain live virus, so they cannot replicate or shed like live-attenuated vaccines (e.g., MMR, oral polio). Spike protein production is localised (mostly muscle), transient, and in tiny amounts. But all of these assumptions have come under question, especially the idea that the mRNA stays at the injection site. If the mainstream can be wrong about so much, I expect them to be wrong about shedding as well.
https://www.midwesterndoctor.com/p/what-we-now-know-about-covid-vaccine