I have been strongly against alcohol consumption all of my life, and my mother and grandmother were in the Temperance League. The aim was to restore moral control to men, as alcohol was seen as not merely a physical problem but a moral one as well. It was no coincidence that there are spirits,’ the strongest form of alcohol. Evil spirits, in fact, as my grandmother called them. Even though the temperance movement has been defeated by the degeneracy of the times, the health defects of alcohol are becoming more apparent, these ranging from harm to most of the body’s organs, but especially the brain:
http://www.collective-evolution.com/2017/12/30/what-alcohol-consumption-does-to-your-brain/
An article in the British Medical Journal of 2017 had this to say about the neurological effects of alcohol on the human brain:
“Even moderate drinking is linked to pathological changes in the brain Epidemiological studies often report better heath in moderate drinkers compared with abstainers. Observed first in studies of incidence of myocardial infarction, the “J shaped curve” (describing the graphical appearance of health measures plotted against consumption) reappears in studies of diabetes, stroke, and even chronic widespread pain.As methods of investigating the association between alcohol and health are refined, however, the size of the apparent benefits reduces substantially. Studies using “Mendelian randomisation,” purportedly impervious to confounding or reverse causality, do not support the original claim that moderate drinking improves cardiovascular health.
Regarded as a further example of the J shaped curve, a protective effect of moderate alcohol consumption against “all cause” dementia has been reported. This has not been underpinned by a convincing neural correlate, however, and it is here that the linked study by Topiwala and colleagues (doi:10.1136/bmj.j2353) is particularly ambitious. In their prospective cohort of 550 civil servants, none of whom were alcohol dependent, the authors repeatedly assessed alcohol consumption and cognition over 30 years. Participants underwent brain imaging at the most recent review, enabling examination of relations between average alcohol use, cognition, and brain structure.
After adjustment for numerous potential confounders, alcohol use was associated with reduced right hippocampal volume in a dose dependent manner; even moderate drinkers (classified as up to 21 units a week for men at the time of the study) were three times more likely to have hippocampal atrophy than abstainers, and very light drinking (1-6 units a week) conferred no protection relative to abstinence. Higher alcohol consumption was also associated with reduced white matter integrity and faster decline in lexical fluency, a test of “executive function.”
With increasing longevity, maintenance of brain health into older age is the key priority of our time. Leaving aside the human cost of dementia, care of cognitively impaired older people is a looming financial crisis, prompting politicians to consider controversial and deeply unpopular policy decisions. Alcohol dependence is already established as a major cause of dementia, alcohol related brain damage (ARBD) accounts for possibly 10% of early onset dementia and potentially 10-24% of dementia cases in nursing homes.
Existing on a spectrum of severity, alcohol related brain damage typically involves relatively young people, often in their 40s or 50s, meaning the more severely affected require decades of institutional care. While alcohol related brain damage generally afflicts malnourished drinkers consuming very high levels of alcohol, some degree of potentially reversible cognitive impairment is detectable in most people starting treatment for alcohol dependence. Alcohol can be the primary cause of cognitive impairment in some individuals, but it is a likely contributor to cognitive decline in many more.
The chief medical officer recently changed guidance for low risk drinking in men, reducing the recommended maximum intake from 21 to 14 units a week. This was because of accumulating evidence that even light drinking increases the risk of various malignancies. The relation between alcohol and brain health is more complex than the relation between alcohol and cancer. While there is almost universal agreement that heavy drinking is associated with cognitive impairment, numerous observational studies do report that light to moderate consumption is associated with a reduced risk of all cause dementia.
While concerns about confounding and inconsistencies between studies make it difficult to define what level of intake is “optimal” for cognition, it seems to be low; in these studies around a unit a day is associated with the lowest risk of dementia, with risk for drinkers clearly exceeding abstainers by 4 units a day. Topiwala and colleagues’ report of adverse effects at even lower levels of intake, coupled with the finding that drinking more than 14 units a week was associated with both brain pathology and cognitive decline, provides further support for the chief medical officer’s recent decision.
How should this paper inform discussions with patients? It certainly strengthens the view that if alcohol does confer beneficial effects on health, the link is probably confined to low intakes of no more than a unit a day. Even this level of consumption carries risk relative to abstinence for conditions such as breast cancer, and the evidence of benefit is certainly not strong enough to justify advising abstainers to drink.”
http://www.bmj.com/content/357/bmj.j2645
As hard as it may be, it is best to avoid drinking grog completely. Various fruit juices can deliver all the antioxidant benefits you need, and more. Keep your soul pure.