Many good things come from the sea, and sea weed, of various types, may hold the key to holding back dementia:
“Research has shown that certain seaweeds have the potential to prevent the onset of Parkinson’s disease. The study, published in BMC Complementary and Alternative Medicine, looked at the ability of antioxidant-rich seaweeds to protect brain cells from the neurotoxin 6-hydroxydopamine (6-OHDA, also known as oxidopamine), a chemical used to simulate Parkinson’s disease. In the study, researchers from the Polytechnic Institute of Leiria in Portugal tested this theory using the human neuroblastoma cell line SH-SY5Y, including its associated intracellular signaling pathways, and conducted an MTT assay to determine cell viability. In addition, the group assessed the intracellular signaling pathways hydrogen peroxide (H2O2) production, changes in the mitochondrial membrane potential, and Caspase-3 activity. These parameters determine how healthy the SH-SY5Y cells are. Changes in these parameters affect cell viability.
The team used seaweeds known to have potent antioxidant activity in the study, including peacock’s tail (Padina pavonica), Japanese wireweed (Sargassum muticum), furbellow (Saccorhiza polyschides), velvet horn (Codium tomentosum), and green alga (Ulva compressa). From the assays, the researchers noted that cell death occurred after being exposed to oxidopamine. The presence of oxidopamine caused an increase in H2O2 production, the depolarization of mitochondrial membrane potential, and the increase in Caspase-3 activity, decreasing cell viability. Oxidative stress, mitochondrial and lysosomal dysfunctions, neuroinflammatory processes, and the formation of pathologic inclusions add to nerve cell death in Parkinson’s disease."
Hopefully there may be supplements of this available soon, if they are not already available now. All we need to do then is to remember to take them! That is, if we even get to first base and remember the name of the sea weed.